Wednesday, March 31, 2010

See bacterial invasion with your own eyes!

Posted on 7:16 PM by Charlie Milwall

Here is a confocal microscopy movie of a cell that's expressing a particular protein that is tagged with a green fluorescent protein (GFP) from jellyfish. The cell is then infected with bacteria (appearing in red). Note that as the each bacterial particle lands, the green host proteins accumulate at the base. This accumulation only occurred where the bacterium landed, indicating that there is a "rercruitment" at the landing site of this GFP-tagged protein. This recruitment implies a role for this host protein in bacterial invasion, and that the bacteria somehow usurps this protein to facilitate infection. A nice demonstration of how bacteria hijacks the host cell components.

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